Publikationen von Mitarbeitern und Doktoranden des IMIBE (2017)

Originalarbeiten in Zeitschriften

Akmatov MK, Koch N, Vital M, Ahrens W, Flesch-Janys D, Fricke J, et al. Determination of nasal and oropharyngeal microbiomes in a multicenter population-based study - findings from Pretest 1 of the German National Cohort. Sci Rep. 2017;7(1):1855.

Akmatov MK, Röber N, Ahrens W, Flesch-Janys D, Fricke J, Greiser H, et al. Anti-nuclear autoantibodies in the general German population: prevalence and lack of association with selected cardiovascular and metabolic disorders-findings of a multicenter population-based study. Arthritis Res Ther. 2017;19(1):127.

Aung T, Ozaki M, Lee MC, Schlötzer-Schrehardt U, Thorleifsson G, Mizoguchi T, et al. Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci. Nat Genet. 2017;49(7):993-1004.

Azizy O, Rammos C, Lehmann N, Rassaf T, Kälsch H. Percutaneous closure of the left atrial appendage in patients with diabetes mellitus. Diab Vasc Dis Res. 2017;14(5):407-14.

Becker JC, Stang A, DeCaprio JA, Cerroni L, Lebbé C, Veness M, et al. Merkel cell carcinoma. Nat Rev Dis Primers. 2017;3:17077.

Behrens T, Rabstein S, Wichert K, Erbel R, Eisele L, Arendt M, et al. Shift work and the incidence of prostate cancer: a 10-year follow-up of a German population-based cohort study. Scand J Work Environ Health. 2017;43(6):560-8.

Birdir C, Fryze J, Nießen S, Schmidt M, Köninger A, Kimmig R, et al. Impact of maternal serum levels of Visfatin, AFP, PAPP-A, sFlt-1 and PlGF at 11-13 weeks gestation on small for gestational age births. J Matern Fetal Neonatal Med. 2017;30(6):629-34.

Bonberg N, Pesch B, Ulrich N, Moebus S, Eisele L, Marr A, et al. The distribution of blood concentrations of lead (Pb), cadmium (Cd), chromium (Cr) and manganese (Mn) in residents of the German Ruhr area and its potential association with occupational exposure in metal industry and/or other risk factors. Int J Hyg Environ Health. 2017;220(6):998-1005.

Bornemann L, Sobczak C, Jockel KH, Gothert J, Schuster M, Gunzer M. Introduction of 2D human leucocyte migration assays suited for the application in the clinical setup. Eur J Immunol. 2017;47 2:232-.

Brand T, Samkange-Zeeb F, Ellert U, Keil T, Krist L, Dragano N, et al. Acculturation and health-related quality of life: results from the German National Cohort migrant feasibility study. Int J Public Health. 2017;62(5):521-9.

Casjens S, Pesch B, Robens S, Kendzia B, Behrens T, Weiss T, et al. Associations between former exposure to manganese and olfaction in an elderly population: Results from the Heinz Nixdorf Recall Study. Neurotoxicology. 2017;58:58-65.

Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, et al. Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nat Genet. 2017;49(6):946-52.

Cordes J, Bechdolf A, Engelke C, Kahl KG, Balijepalli C, Lösch C, et al. Prevalence of metabolic syndrome in female and male patients at risk of psychosis. Schizophr Res. 2017;181:38-42.

da Silva Filho MI, Försti A, Weinhold N, Meziane I, Campo C, Huhn S, et al. Genome-wide association study of immunoglobulin light chain amyloidosis in three patient cohorts: comparison with myeloma. Leukemia. 2017;31(8):1735-42.

Dötsch A, Eisele L, Rabeling M, Rump K, Walstein K, Bick A, et al. Hypoxia Inducible Factor-2 Alpha and Prolinhydroxylase 2 Polymorphisms in Patients with Acute Respiratory Distress Syndrome (ARDS). Int J Mol Sci. 2017;18(6).

Dragano N, Siegrist J, Nyberg ST, Lunau T, Fransson EI, Alfredsson L, et al. Effort-Reward Imbalance at Work and Incident Coronary Heart Disease: A Multicohort Study of 90,164 Individuals. Epidemiology. 2017;28(4):619-26.

Duhrsen U, Huttmann A, Muller S, Hertenstein B, Thomssen H, Kotzerke J, et al. Positron-emission tomography-guided therapy of aggressive non-Hodgkin lymphomas -final results of the PETAL trial. Oncology Research and treatment. 2017;40 3:202-3.

Duhrsen U, Huttmann A, Muller S, Hertenstein B, Thomssen H, Kotzerke J, et al. Positron-emission tomography-guided therapy of aggressive non-Hodgkin lymphomas -final results of the PETAL trial. Oncology Research and treatment. 2017;40 3:202-3.

Erbel R. [Echocardiography : Important diagnostic pillar in cardiology]. Herz. 2017;42(3):229-31.

Erbel R, Churzidse S. Calcification of the aortic wall indicates risk but not beyond current clinically used risk factors assessment. Atherosclerosis. 2017;257:256-8.

Esser S, Arendt M, Schulze C, Holzendorf V, Brockmeyer NH, Jockel KH, et al. More and earlier cardiovascular events (CVEs) and shorter overall survival (OS) in HIV-positive patients (HIV positive) compared to the general population differ by sex. J Int AIDS Soc. 2017;20 5:70-1.

Fischer J, Degenhardt F, Hofmann A, Redler S, Basmanav FB, Heilmann-Heimbach S, et al. Genomewide analysis of copy number variants in alopecia areata in a Central European cohort reveals association with MCHR2. Exp Dermatol. 2017;26(6):536-41.

Forstner AJ, Hecker J, Hofmann A, Maaser A, Reinbold CS, Mühleisen TW, et al. Identification of shared risk loci and pathways for bipolar disorder and schizophrenia. PLoS ONE. 2017;12(2):e0171595.

Frölich S, Lehmann N, Weyers S, Wahl S, Dragano N, Budde T, et al. Association of dietary patterns with five-year degree and progression of coronary artery calcification in the Heinz Nixdorf Recall study. Nutr Metab Cardiovasc Dis. 2017;27(11):999-1007.

Geisel MH, Bauer M, Hennig F, Hoffmann B, Lehmann N, Möhlenkamp S, et al. Comparison of coronary artery calcification, carotid intima-media thickness and ankle-brachial index for predicting 10-year incident cardiovascular events in the general population. Eur Heart J. 2017;38(23):1815-22.

Genon S, Li H, Fan L, Müller VI, Cieslik EC, Hoffstaedter F, et al. The Right Dorsal Premotor Mosaic: Organization, Functions, and Connectivity. Cereb Cortex. 2017;27(3):2095-110.

Gorla R, Erbel R, Kahlert P, Tsagakis K, Jakob H, Mahabadi AA, et al. Accuracy of a diagnostic strategy combining aortic dissection detection risk score and D-dimer levels in patients with suspected acute aortic syndrome. Eur Heart J Acute Cardiovasc Care. 2017;6(5):371-8.

Gorla R, Erbel R, Kahlert P, Tsagakis K, Jakob H, Mahabadi AA, et al. Diagnostic role and prognostic implications of D-dimer in different classes of acute aortic syndromes. Eur Heart J Acute Cardiovasc Care. 2017;6(5):379-88.

Gorla R, Tsagakis K, Horacek M, Mahabadi AA, Kahlert P, Jakob H, et al. Impact of Preoperative Anemia and Postoperative Hemoglobin Drop on the Incidence of Acute Kidney Injury and In-Hospital Mortality in Patients With Type B Acute Aortic Syndromes Undergoing Thoracic Endovascular Aortic Repair. Vasc Endovascular Surg. 2017;51(3):131-8.

Hebebrand J, Hamelmann E, Hartmann A, Holtmann M, Jöckel KH, Kremer U, et al. [Current Practice of Pre- and Postnatal Screening and Future Developments for Evidence Based Guidelines]. Klin Padiatr. 2017;229(1):2-13.

Heilmann-Heimbach S, Herold C, Hochfeld LM, Hillmer AM, Nyholt DR, Hecker J, et al. Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness. Nat Commun. 2017;8:14694.

Heilmann-Heimbach S, Pechlivanis S, Hochfeld LM, Mahabadi AA, Erbel R, Jokel K, et al. Male-pattern baldness and its association with coronary heart disease. J Invest Dermatol. 2017;137 2(10):S239-S.

Husmann C, Frank M, Schmidt B, Jöckel KH, Antel J, Reissner V, et al. Low 25(OH)-vitamin D concentrations are associated with emotional and behavioral problems in German children and adolescents. PLoS ONE. 2017;12(8):e0183091.

Jannusch K, Jockwitz C, Bidmon HJ, Moebus S, Amunts K, Caspers S. A Complex Interplay of Vitamin B1 and B6 Metabolism with Cognition, Brain Structure, and Functional Connectivity in Older Adults. Front Neurosci. 2017;11:596.

Jockwitz C, Caspers S, Lux S, Eickhoff SB, Jütten K, Lenzen S, et al. Influence of age and cognitive performance on resting-state brain networks of older adults in a population-based cohort. Cortex. 2017;89:28-44.

Kälsch H, Lehmann N, Moebus S, Hoffmann B, Stang A, Jöckel KH, et al. Aortic Calcification Onset and Progression: Association With the Development of Coronary Atherosclerosis. J Am Heart Assoc. 2017;6(4).

Kara K, Mahabadi AA, Weimar C, Winkler A, Neumann T, Kälsch H, et al. N-Terminal Pro-B Type Natriuretic Peptide is Associated with Mild Cognitive Impairment in the General Population. J Alzheimers Dis. 2017;55(1):359-69.

Katalinic A, Krause G, Geyer S, Moebus S. [Kein Titel angegeben]. Gesundheitswesen. 2017;79(8-09):592-3.

Kendzia B, Pesch B, Koppisch D, Van Gelder R, Pitzke K, Zschiesche W, et al. Modelling of occupational exposure to inhalable nickel compounds. J Expo Sci Environ Epidemiol. 2017;27(4):427-33.

Köninger A, Schmidt B, Damaske D, Birdir C, Enekwe A, Kimmig R, et al. Follistatin during pregnancy and its potential role as an ovarian suppressing agent. Eur J Obstet Gynecol Reprod Biol. 2017;212:150-4.

Kowall B, Lehmann N, Mahabadi AA, Moebus S, Budde T, Seibel R, et al. Progression of coronary artery calcification is stronger in poorly than in well controlled diabetes: Results from the Heinz Nixdorf Recall Study. J Diabetes Complications. 2017;31(1):234-40.

Kowall B, Rathmann W, Stang A, Bongaerts B, Kuss O, Herder C, et al. Perceived risk of diabetes seriously underestimates actual diabetes risk: The KORA FF4 study. PLoS ONE. 2017;12(1):e0171152.

Kowall B, Stang A. Measurement is always better than self-report: is it that easy? Sleep Med. 2017;38:157.

Kuklik N, Stausberg J, Jöckel KH. Adverse drug events in German hospital routine data: A validation of International Classification of Diseases, 10th revision (ICD-10) diagnostic codes. PLoS ONE. 2017;12(11):e0187510.

Laube T, Brockmann C, Lehmann N, Bornfeld N. Pseudophakic retinal detachment in young-aged patients. PLoS ONE. 2017;12(8):e0184187.

Law PJ, Sud A, Mitchell JS, Henrion M, Orlando G, Lenive O, et al. Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci. Sci Rep. 2017;7:41071.

Mahabadi AA, Möhlenkamp S, Lehmann N, Kälsch H, Dykun I, Pundt N, et al. CAC Score Improves Coronary and CV Risk Assessment Above Statin Indication by ESC and AHA/ACC Primary Prevention Guidelines. JACC Cardiovasc Imaging. 2017;10(2):143-53.

Mayer-Berger W, Pieper C, Klemm S, Schroer S. Secondary Prevention in Patients with arterial Hypertension for the sustained Implementation of a Yoga Intervention (Mind-Body-Therapy) - a randomized controlled Study. Z Psychosom Med Psychother. 2017;63(1):88-9.

McDonald WC, Banerji N, McDonald KN, Ho B, Macias V, Kajdacsy-Balla A. Steroidogenic Factor 1, Pit-1, and Adrenocorticotropic Hormone: A Rational Starting Place for the Immunohistochemical Characterization of Pituitary Adenoma. Arch Pathol Lab Med. 2017;141(1):104-12.

Meziane I, Huhn S, Filho M, Weinhold N, Campo C, Nickel J, et al. Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts. Haematologica. 2017;102(10):e411-e4.

Moebus S, Kuhn J, Hoffmann W. [Big Data and Public Health - Results of the Working Group 1 of the Forum Future Public Health, Berlin 2016]. Gesundheitswesen. 2017;79(11):901-5.

Morawa E, Dragano N, Jöckel KH, Moebus S, Brand T, Erim Y. Somatization among persons with Turkish origin: Results of the pretest of the German National Cohort Study. J Psychosom Res. 2017;96:1-9.

Muehleisen T, Teumer A, Wittfeld K, Jockwitz C, van der Auwera S, Herms S, et al. GENOME-WIDE ASSOCIATION STUDY IMPLICATES LOW-FREQUENCY AND COMMON VARIANTS IN BRAIN FOLDING. Eur Neuropsychopharmacol. 2017;27 2:S230-S.

Mühlig Y, Scherag A, Bickenbach A, Giesen U, Holl R, Holle R, et al. A Structured, Manual-Based Low-Level Intervention vs. Treatment as Usual Evaluated in a Randomized Controlled Trial for Adolescents with Extreme Obesity - the STEREO Trial. Obes Facts. 2017;10(4):341-52.

Munz M, Willenborg C, Richter GM, Jockel-Schneider Y, Graetz C, Staufenbiel I, et al. A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis. Hum Mol Genet. 2017;26(13):2577-88.

Niedworok C, Tschirdewahn S, Reis H, Lehmann N, Szücs M, Nyirády P, et al. Serum Chromogranin A as a Complementary Marker for the Prediction of Prostate Cancer-Specific Survival. Pathol Oncol Res. 2017;23(3):643-50.

Oeverhaus M, Witteler T, Lax H, Esser J, Führer D, Eckstein A. Combination Therapy of Intravenous Steroids and Orbital Irradiation is More Effective Than Intravenous Steroids Alone in Patients with Graves´ Orbitopathy. Horm Metab Res. 2017;49(10):739-47.

Olsson AC, Vermeulen R, Schüz J, Kromhout H, Pesch B, Peters S, et al. Exposure-Response Analyses of Asbestos and Lung Cancer Subtypes in a Pooled Analysis of Case-Control Studies. Epidemiology. 2017;28(2):288-99.

Orban E, Arendt M, Hennig F, Lucht S, Eisele L, Jakobs H, et al. Is long-term particulate matter and nitrogen dioxide air pollution associated with incident monoclonal gammopathy of undetermined significance (MGUS)? An analysis of the Heinz Nixdorf Recall study. Environ Int. 2017;108:237-45.

Orban E, Sutcliffe R, Dragano N, Jöckel KH, Moebus S. Residential Surrounding Greenness, Self-Rated Health and Interrelations with Aspects of Neighborhood Environment and Social Relations. J Urban Health. 2017;94(2):158-69.


Pelzer BW, Arendt M, Siegmund JM, Eisele L, Moebus S, Jockel KH, et al. Longitudinal analysis of light-chain monoclonal gammopathy of undetermined significance-10-year follow up of the population-based Heinz Nixdorf Recall study. Oncology Research and treatment. 2017;40 3:81-.

Pesch B, Casjens S, Weiss T, Kendzia B, Arendt M, Eisele L, et al. Occupational Exposure to Manganese and Fine Motor Skills in Elderly Men: Results from the Heinz Nixdorf Recall Study. Ann Work Expo Health. 2017;61(9):1118-31.

Pläschke RN, Cieslik EC, Müller VI, Hoffstaedter F, Plachti A, Varikuti DP, et al. On the integrity of functional brain networks in schizophrenia, Parkinson´s disease, and advanced age: Evidence from connectivity-based single-subject classification. Hum Brain Mapp. 2017;38(12):5845-58.

Radunz S, Saner FH, Treckmann J, Rekowski J, Theysohn JM, Muller S, et al. Hepatic artery and biliary complications in liver transplant recipients with radioembolization bridging treatment for hepatocellular carcinoma. Clin Transplant. 2017;31(11):e13096.

Reinsch N, Arendt M, Geisel MH, Schulze C, Holzendorf V, Warnke A, et al. Prolongation of the QTc interval in HIV-infected individuals compared to the general population. Infection. 2017;45(5):659-67.

Riedel N, van Kamp I, Kockler H, Scheiner J, Moebus S, Reineke B, et al. Access to a quiet side, green near the dwelling and perceived control over traffic noise exposure. Eur J Public Health. 2017;27 3:110-.

Rieg S, Joost I, Weiß V, Peyerl-Hoffmann G, Schneider C, Hellmich M, et al. Combination antimicrobial therapy in patients with Staphylococcus aureus bacteraemia-a post hoc analysis in 964 prospectively evaluated patients. Clin Microbiol Infect. 2017;23(6):406.e1-.e8.

Schramm S, Lahner H, Jöckel KH, Erbel R, Führer D, Moebus S, et al. Impact of season and different vitamin D thresholds on prevalence of vitamin D deficiency in epidemiological cohorts-a note of caution. Endocrine. 2017;56(3):658-66.

Schröder C, Leitão E, Wallner S, Schmitz G, Klein-Hitpass L, Sinha A, et al. Regions of common inter-individual DNA methylation differences in human monocytes: genetic basis and potential function. Epigenetics Chromatin. 2017;10(1):37.

Schulz H, Ruppert AK, Herms S, Wolf C, Mirza-Schreiber N, Stegle O, et al. Genome-wide mapping of genetic determinants influencing DNA methylation and gene expression in human hippocampus. Nat Commun. 2017;8(1):1511.

Schweyen R, Stang A, Wienke A, Eckert A, Kuhnt T, Hey J. The influence of dental treatment on the development of osteoradionecrosis after radiotherapy by modern irradiation techniques. Clin Oral Investig. 2017;21(8):2499-508.

Scott RA, Scott LJ, Mägi R, Marullo L, Gaulton KJ, Kaakinen M, et al. An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes. 2017;66(11):2888-902.

Shusterman A, Munz M, Richter G, Jepsen S, Lieb W, Krone B, et al. The PF4/PPBP/CXCL5 Gene Cluster Is Associated with Periodontitis. J Dent Res. 2017;96(8):945-52.

Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer´s disease. Nat Genet. 2017;49(9):1373-84.

Sluik D, Jankovic N, Hughes M, O´Doherty MG, Schöttker B, Drygas W, et al. Alcoholic beverage preference and diabetes incidence across Europe: the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES) project. Eur J Clin Nutr. 2017;71(5):659-68.

Stang A. Statistics Visualization not Very Successful. Dtsch Arztebl Int. 2017;114(41):689.

Stang A, Bärninghausen T. [Medical Progress ans Public Health - Results of the Working Group 4 of the Forum Future Public Health, Berlin]. Gesundheitswesen. 2017;79(11):913-5.

Stang A, Deckert M, Poole C, Rothman KJ. Statistical inference in abstracts of major medical and epidemiology journals 1975-2014: a systematic review. Eur J Epidemiol. 2017;32(1):21-9.


Sud A, Thomsen H, Law PJ, Försti A, Filho M, Holroyd A, et al. Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility. Nat Commun. 2017;8(1):1892.

Temming P, Arendt M, Viehmann A, Eisele L, Le Guin CH, Schündeln MM, et al. Incidence of second cancers after radiotherapy and systemic chemotherapy in heritable retinoblastoma survivors: A report from the German reference center. Pediatr Blood Cancer. 2017;64(1):71-80.

Thomsen H, Campo C, Weinhold N, da Silva Filho MI, Pour L, Gregora E, et al. Genomewide association study on monoclonal gammopathy of unknown significance (MGUS). Eur J Haematol. 2017;99(1):70-9.

Treutlein J, Frank J, Streit F, Reinbold CS, Juraeva D, Degenhardt F, et al. Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis. Genes (Basel). 2017;8(7):183.

Trocchi P, Girndt M, Scheidt-Nave C, Markau S, Stang A. Impact of the estimation equation for GFR on population-based prevalence estimates of kidney dysfunction. BMC Nephrol. 2017;18(1):341.

Trocchi P, Holzhausen HJ, Löning T, Böcker W, Schmidt-Pokrzywniak A, Thomssen C, et al. Intraobserver Agreement on Histopathologic Evaluations of Core Breast Biopsies. Breast J. 2017;23(2):215-9.

Tzivian L, Jokisch M, Winkler A, Weimar C, Hennig F, Sugiri D, et al. Associations of long-term exposure to air pollution and road traffic noise with cognitive function-An analysis of effect measure modification. Environ Int. 2017;103:30-8.
Verma N, Pink M, Boland S, Rettenmeier AW, Schmitz-Spanke S. Benzo[a]pyrene-induced metabolic shift from glycolysis to pentose phosphate pathway in the human bladder cancer cell line RT4. Sci Rep. 2017;7(1):9773.

Vijayakrishnan J, Kumar R, Henrion MY, Moorman AV, Rachakonda PS, Hosen I, et al. A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1. Leukemia. 2017;31(3):573-9.

Walendy V, Stang A. Clinical management of unruptured intracranial aneurysm in Germany: a nationwide observational study over a 5-year period (2005-2009). BMJ Open. 2017;7(1):e012294.

Webb TR, Erdmann J, Stirrups KE, Stitziel NO, Masca NG, Jansen H, et al. Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. J Am Coll Cardiol. 2017;69(7):823-36.

Weimar C, Bilbilis K, Rekowski J, Holst T, Beyersdorf F, Breuer M, et al. Safety of Simultaneous Coronary Artery Bypass Grafting and Carotid Endarterectomy Versus Isolated Coronary Artery Bypass Grafting: A Randomized Clinical Trial. Stroke. 2017;48(10):2769-75.

Yano Y, O´Donnell CJ, Kuller L, Kavousi M, Erbel R, Ning H, et al. Association of Coronary Artery Calcium Score vs Age With Cardiovascular Risk in Older Adults: An Analysis of Pooled Population-Based Studies. JAMA Cardiol. 2017;2(9):986-94.

Ziese T, Moebus S. [New Ways of Communication - Results of the Working Group 5 of the Forum Future Public Health, Berlin 2016]. Gesundheitswesen. 2017;79(11):916-8.