Publikationen von Mitarbeitern und Doktoranden des IMIBE (2012)

Originalarbeiten in Zeitschriften

Andrich S, Dragano N, Mohlenkamp S, Schmermund A, Lehmann N, Slomiany U, et al. Relationship between moderate physical Activity and the extent of coronary Calcification - Results of the Heinz Nixdorf Recall Study. Gesundheitswesen. 2012;74(8-9):543-.

Behrens T, Lynge E, Cree I, Lutz JM, Eriksson M, Guénel P, et al. Pesticide exposure in farming and forestry and the risk of uveal melanoma. Cancer Causes Control. 2012;23(1):141-51.

Bokhof B, Buyken AE, Do?an C, Karabo?a A, Kaiser J, Sonntag A, et al. Validation of protein and potassium intakes assessed from 24 h recalls against levels estimated from 24 h urine samples in children and adolescents of Turkish descent living in Germany: results from the EVET! Study. Public Health Nutr. 2012;15(4):640-7.

Bradfield JP, Taal HR, Timpson NJ, Scherag A, Lecoeur C, Warrington NM, et al. A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet. 2012;44(5):526-31.

Broderick P, Chubb D, Johnson DC, Weinhold N, Försti A, Lloyd A, et al. Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk. Nat Genet. 2012;44(1):58-61.


Christoph DC, Kasper S, Gauler TC, Loesch C, Engelhard M, Theegarten D, et al.?V-tubulin expression is associated with outcome following taxane-based chemotherapy in non-small cell lung cancer. Br J Cancer. 2012;107(5):823-30.

Cyrys J, Eeftens M, Heinrich J, Ampe C, Armengaud A, Beelen R, et al. Variation of NO2 and NOx concentrations between and within 36 European study areas: Results from the ESCAPE study. Atmos Environ (1994). 2012;62:374-90.

Degenhardt F, Priebe L, Herms S, Mattheisen M, Mühleisen TW, Meier S, et al. Association between copy number variants in 16p11.2 and major depressive disorder in a German case-control sample. Am J Med Genet B Neuropsychiatr Genet. 2012;159B(3):263-73.

Dlugaj M, Gerwig M, Wege N, Siegrist J, Mann K, Bröcker-Preuß M, et al. Elevated Levels of High-Sensitivity C-Reactive Protein are Associated with Mild Cognitive Impairment and its Subtypes: Results of a Population-Based Case-Control Study. J Alzheimers Dis. 2012;28(3):503-14.

Eeftens M, Beelen R, de Hoogh K, Bellander T, Cesaroni G, Cirach M, et al. Development of Land Use Regression models for PM(2.5), PM(2.5) absorbance, PM(10) and PM(coarse) in 20 European study areas; results of the ESCAPE project. Environ Sci Technol. 2012;46(20):11195-205.

Eisele L, Dürig J, Hüttmann A, Dührsen U, Assert R, Bokhof B, et al. Prevalence and progression of monoclonal gammopathy of undetermined significance and light-chain MGUS in Germany. Ann Hematol. 2012;91(2):243-8.

Erbel R, Eisele L, Moebus S, Dragano N, Möhlenkamp S, Bauer M, et al. [The Heinz Nixdorf Recall study]. Bundesgesundheitsblatt Gesundheitsforschung, Gesundheitsschutz. 2012;55(6-7):809-15.
Erbel R, Lehmann N, Möhlenkamp S, Churzidse S, Bauer M, Kälsch H, et al. Subclinical Coronary Atherosclerosis Predicts Cardiovascular Risk in Different Stages of Hypertension: Result of the Heinz Nixdorf Recall Study. Hypertension. 2012;59(1):44-53.
Fransson EI, Heikkilä K, Nyberg ST, Zins M, Westerlund H, Westerholm P, et al. Job Strain as a Risk Factor for Leisure-Time Physical Inactivity: An Individual-Participant Meta-Analysis of Up to 170,000 Men and Women: The IPD-Work Consortium. Am J Epidemiol. 2012;176(12):1078-89.

Gerrish A, Russo G, Richards A, Moskvina V, Ivanov D, Harold D, et al. The role of variation at A?PP, PSEN1, PSEN2, and MAPT in late onset Alzheimer´s disease. J Alzheimers Dis. 2012;28(2):377-87.

Gobel M, Eisele L, Huttmann A, Bergmann M, Busch R, Stilgenbauer S, et al. Progranulin plasma concentration is a novel independent prognostic marker in chronic lymphocytic leukemia. Onkologie. 2012;35 6:100-.

Grabellus F, Stylianou E, Umutlu L, Sheu SY, Lehmann N, Taeger G, et al. Size-Based Clinical Response Evaluation is Insufficient to Assess Clinical Response of Sarcomas Treated with Isolated Limb Perfusion with TNF-? and Melphalan. Ann Surg Oncol. 2012;19(11):3375-85.

Graf D, Helmich-Kapp B, Graf S, Veit F, Lehmann N, Mann K. [Functional activity of autonomous adenoma in Germany]. Dtsch Med Wochenschr. 2012;137(41):2089-92.
Gronewold J, Bauer M, Lehmann N, Kroger K, Moebus S, Jockel KH, et al. Ankle brachial index is a strong predictor of stroke events in the general population. Eur J Neurol. 2012;19 1:158-.

Hanoun M, Eisele L, Suzuki M, Greally JM, Hüttmann A, Aydin S, et al. Epigenetic silencing of the circadian clock gene CRY1 is associated with an indolent clinical course in chronic lymphocytic leukemia. PLoS ONE. 2012;7(3):e34347.
Hauth EAM, Berkemeyer S, Jaeger H, Forsting M, Hoffmann B, Jockel KH. Epidemiological Follow-up 15 Years after the Breast Cancer Scandal in Essen. Geburtshilfe Frauenheilkd. 2012;72(6):513-22.

Håvik B, Degenhardt FA, Johansson S, Fernandes CP, Hinney A, Scherag A, et al. DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder. PLoS ONE. 2012;7(4):e35424.

Heikkilä K, Nyberg ST, Fransson EI, Alfredsson L, De Bacquer D, Bjorner JB, et al. Job strain and alcohol intake: a collaborative meta-analysis of individual-participant data from 140,000 men and women. PLoS ONE. 2012;7(7):e40101.

Heikkilä K, Nyberg ST, Fransson EI, Alfredsson L, De Bacquer D, Bjorner JB, et al. Job strain and tobacco smoking: an individual-participant data meta-analysis of 166,130 adults in 15 European studies. PLoS ONE. 2012;7(7):e35463.

Heinemann A, Zhao F, Pechlivanis S, Eberle J, Steinle A, Diederichs S, et al. Tumor suppressive microRNAs miR-34a/c control cancer cell expression of ULBP2, a stress-induced ligand of the natural killer cell receptor NKG2D. Cancer Res. 2012;72(2):460-71.

Hermann DM, Gronewold J, Lehmann N, Seidel UK, Möhlenkamp S, Weimar C, et al. Intima-media thickness predicts stroke risk in the Heinz Nixdorf Recall study in association with vascular risk factors, age and gender. Atherosclerosis. 2012;224(1):84-9.

Heumüller S, Stausberg J, Jöckel KH. [Neurological complex treatment: impact on mortality in the first year and costs for statutory health insurance]. Fortschr Neurol Psychiatr. 2012;80(10):593-8.

Hinney A, Scherag A, Jarick I, Albayrak O, Putter C, Pechlivanis S, et al. Genome-wide association study in German patients with attention deficit/hyperactivity disorder (vol 156B, pg 888, 2011). Am J Med Genet B Neuropsychiatr Genet. 2012;159B(4):476-.

Hoffmann B, Dragano N, Schweitzer-Krantz S. Living situation, occupation and health-related quality of life in adult patients with classic galactosemia. J Inherit Metab Dis. 2012;35(6):1051-8.

Hollingworth P, Sweet R, Sims R, Harold D, Russo G, Abraham R, et al. Genome-wide association study of Alzheimer´s disease with psychotic symptoms. Mol Psychiatry. 2012;17(12):1316-27.

Horacek M, Möhlenkamp S, Mahabadi AA, Churzidse S, Moebus S, Jöckel KH, et al. [Prevalence of arterial hypertension in the population of Western Germany: Heinz Nixdorf Recall Study]. Herz. 2012;37(7):721-7.

Houshmand M, Holtfreter B, Berg MH, Schwahn C, Meisel P, Biffar R, et al. Refining definitions of periodontal disease and caries for prediction models of incident tooth loss. J Clin Periodontol. 2012;39(7):635-44.

Ichimura A, Hirasawa A, Poulain-Godefroy O, Bonnefond A, Hara T, Yengo L, et al. Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. Nature. 2012;483(7389):350-4.

Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, et al. Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet. 2012;44(5):539-44.

Jacobs DI, Walsh KM, Wrensch M, Wiencke J, Jenkins R, Houlston RS, et al. Leveraging ethnic group incidence variation to investigate genetic susceptibility to glioma: a novel candidate SNP approach. Front Genet. 2012;3:203.

Kaelsch H, Berg MH, Lehmann N, Mahabadi AA, Kara K, Moehlenkamp S, et al. Association of thoracic aortic calcification with incident myocardial infarction and all-cause mortality in the general population: the Heinz Nixdorf Recall Study. Eur Heart J. 2012;33 1:953-.

Kahl KG, Greggersen W, Schweiger U, Cordes J, Balijepalli C, Lösch C, et al. Prevalence of the metabolic syndrome in unipolar major depression. Eur Arch Psychiatry Clin Neurosci. 2012;262(4):313-20.

Kara K, Mahabadi AA, Berg MH, Lehmann N, Kalsch H, Bauer M, et al. B-Type Natriuretic Peptide: Age and Gender Specific for Risk Stratification in the General Population - The Heinz Nixdorf Recall Study. Circulation. 2012;126 S(21).
Knipp SC, Scherag A, Beyersdorf F, Cremer J, Diener HC, Haverich JA, et al. Randomized comparison of synchronous CABG and carotid endarterectomy vs. isolated CABG in patients with asymptomatic carotid stenosis: the CABACS trial. Int J Stroke. 2012;7(4):354-60.

Knoll N, Volckmar AL, Pütter C, Scherag A, Kleber M, Hebebrand J, et al. The fatty acid amide hydrolase (FAAH) gene variant rs324420 AA/AC is not associated with weight loss in a 1-year lifestyle intervention for obese children and adolescents. Horm Metab Res. 2012;44(1):75-7.


Kunz I, Roggenbuck U, Klevecka V, Musch M, Kroepfl D. Effect of advanced age (>= 70 yrs) on prostate cancer characteristics, survival and postoperative continence in patients undergoing radical prostatectomy. Eur Urol Suppl. 2012;11(1):E1056-U205.


Lauche R, Cramer H, Moebus S, Paul A, Michalsen A, Langhorst J, et al. Results of a 2-week inpatient stay at the department for internal and integrative medicine: an observational study. Evid Based Complement Alternat Med. 2012;2012:875874.

Li R, Brockschmidt FF, Kiefer AK, Stefansson H, Nyholt DR, Song K, et al. Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases. PLoS Genet. 2012;8(5):e1002746.

Mahabadi AA, Berg MH, Lehmann N, Kalsch H, Bauer M, Kara K, et al. Association of pericardial fat with incident myocardial infarction in the general population: the Heinz Nixdorf Recall study. Eur Heart J. 2012;33 1:493-4.

Mahahadi AA, Berg MH, Lehmann N, Kalsch H, Kara K, Bauer M, et al. Association of CT-derived Left Atrial Size with Major Cardiovascular Events in the General Population: The Heinz Nixdorf Recall Study. Circulation. 2012;126 S(21).

Merks BT, Burger H, Willemsen J, van Gool JD, de Jong TP. Melatonin treatment in children with therapy-resistant monosymptomatic nocturnal enuresis. J Pediatr Urol. 2012;8(4):416-20.

Mikat B, Zeller A, Scherag A, Drommelschmidt K, Kimmig R, Schmidt M. ?hCG and PAPP-A in first trimester: predictive factors for preeclampsia? Hypertens Pregnancy. 2012;31(2):261-7.

Morris AP, Voight BF, Teslovich TM, Ferreira T, Segrè AV, Steinthorsdottir V, et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 2012;44(9):981-90.

Mühleisen TW, Mattheisen M, Strohmaier J, Degenhardt F, Priebe L, Schultz CC, et al. Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder. Schizophr Res. 2012;138(1):69-73.
Mühlhaus J, Pütter C, Brumm H, Grallert H, Illig T, Scherag S, et al. Do common variants separate between obese melanocortin-4 receptor gene mutation carriers and non-carriers? The impact of cryptic relatedness. Horm Res Paediatr. 2012;77(6):358-68.
Müller TD, Greene BH, Bellodi L, Cavallini MC, Cellini E, Di Bella D, et al. Fat Mass and Obesity-Associated Gene ( FTO ) in Eating Disorders: Evidence for Association of the rs9939609 Obesity Risk Allele with Bulimia nervosa and Anorexia nervosa. Obes Facts. 2012;5(3):408-19.

Musch M, Roggenbuck U, Davoudi Y, Loewen H, Yanovskiy M, Klevecka V, et al. Robotic-assisted transperitoneal and open surgical retropubic prostatectomy - a single surgeon comparison. Eur Urol Suppl. 2012;11(1):E566-U217.

Nyberg ST, Heikkilä K, Fransson EI, Alfredsson L, De Bacquer D, Bjorner JB, et al. Job strain in relation to body mass index: pooled analysis of 160 000 adults from 13 cohort studies. J Intern Med. 2012;272(1):65-73.

Pesch B, Kendzia B, Gustavsson P, Jöckel KH, Johnen G, Pohlabeln H, et al. Cigarette smoking and lung cancer-relative risk estimates for the major histological types from a pooled analysis of case-control studies. Int J Cancer. 2012;131(5):1210-9.

Peters MA, Wendholt D, Strietholt S, Frank S, Pundt N, Korb-Pap A, et al. The loss of ?2?1 integrin suppresses joint inflammation and cartilage destruction in mouse models of rheumatoid arthritis. Arthritis Rheum. 2012;64(5):1359-68.

Peters S, Kromhout H, Olsson AC, Wichmann HE, Brüske I, Consonni D, et al. Occupational exposure to organic dust increases lung cancer risk in the general population. Thorax. 2012;67(2):111-6.

Pieper C, Kolankowska I, Jöckel KH. Does a screening questionnaire for familial and hereditary colorectal cancer risk work in a health insurance population? Eur J Cancer Care (Engl). 2012;21(6):758-65.

Priebe L, Degenhardt FA, Herms S, Haenisch B, Mattheisen M, Nieratschker V, et al. Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder. Mol Psychiatry. 2012;17(4):421-32.

Putter C, Jockel K-H, Wichmann H-E, Scherag A. Does Size Always Matter? A Simulation Study On The Impact Of Slightly Altered True Genetic Models. Genet Epidemiol. 2012;36(2):168-.

Rath PM, Saner F, Paul A, Lehmann N, Steinmann E, Buer J, et al. Multiplex PCR for rapid and improved diagnosis of bloodstream infections in liver transplant recipients. J Clin Microbiol. 2012;50(6):2069-71.

Reinsch N, Mahabadi AA, Lehmann N, Möhlenkamp S, Hoefs C, Sievers B, et al. Comparison of dual-source and electron-beam CT for the assessment of coronary artery calcium scoring. Br J Radiol. 2012;85(1015):e300-6.

Retz W, Rösler M, Ose C, Scherag A, Alm B, Philipsen A, et al. Multiscale assessment of treatment efficacy in adults with ADHD: A randomized placebo-controlled, multi-centre study with extended-release methylphenidate. World J Biol Psychiatry. 2012;13(1):48-59.

Rezai M, Scherag A, Kessel S, Kimmig R, Kern P. Risk-reducing surgery by skin-sparing mastectomy (SSM) and immediate implant-based reconstruction with and without titanized meshes and quality of life. J Clin Oncol. 2012;30 S(27).

Riedel N, Fuks K, Hoffmann B, Weyers S, Siegrist J, Erbel R, et al. Insomnia and urban neighbourhood contexts--are associations modified by individual social characteristics and change of residence? Results from a population-based study using residential histories. BMC Public Health. 2012;12:810.

Rietschel M, Mattheisen M, Degenhardt F, Genetic R, Outcome in P, Mühleisen TW, et al. Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe. Mol Psychiatry. 2012;17(9):906-17.

Rückert IM, Maier W, Mielck A, Schipf S, Völzke H, Kluttig A, et al. Personal attributes that influence the adequate management of hypertension and dyslipidemia in patients with type 2 diabetes. Results from the DIAB-CORE Cooperation. Cardiovasc Diabetol. 2012;11:120.

Rückert IM, Schunk M, Holle R, Schipf S, Völzke H, Kluttig A, et al. Blood pressure and lipid management fall far short in persons with type 2 diabetes: results from the DIAB-CORE Consortium including six German population-based studies. Cardiovasc Diabetol. 2012;11:50.

Saner FH, Treckmann JW, Geis A, Lösch C, Witzke O, Canbay A, et al. Efficacy and safety of regional citrate anticoagulation in liver transplant patients requiring post-operative renal replacement therapy. Nephrol Dial Transplant. 2012;27(4):1651-7.

Scherag A, Kleber M, Boes T, Kolbe AL, Ruth A, Grallert H, et al. SDCCAG8 obesity alleles and reduced weight loss after a lifestyle intervention in overweight children and adolescents. Obesity (Silver Spring). 2012;20(2):466-70.

Schimming TT, Grabellus F, Roner M, Pechlivanis S, Sucker A, Bielefeld N, et al. pHH3 immunostaining improves interobserver agreement of mitotic index in thin melanomas. Am J Dermatopathol. 2012;34(3):266-9.

Schipf S, Werner A, Tamayo T, Holle R, Schunk M, Maier W, et al. Regional differences in the prevalence of known Type 2 diabetes mellitus in 45-74 years old individuals: results from six population-based studies in Germany (DIAB-CORE Consortium). Diabet Med. 2012;29(7):e88-95.

Schmidt B, Schulz C, Moebus S, Seiwert M, Kolossa-Gehring M, Jöckel KH. [Concept for a German national birth cohort for environmental health research]. Bundesgesundheitsblatt Gesundheitsforschung, Gesundheitsschutz. 2012;55(6-7):852-7.

Schramm S, Lahner H, Jockel KH, Moebus S. Impact of various national and international Limits for Vitamin D DEficiency in a population-based Study. Gesundheitswesen. 2012;74(8-9):587-.

Senska G, Schröder H, Pütter C, Dost P. Significantly reducing post-tonsillectomy haemorrhage requiring surgery by suturing the faucial pillars: a retrospective analysis. PLoS ONE. 2012;7(10):e47874.

Stahl M, Lehmann N, Walz MK, Stuschke M, Wilke H. Prediction of prognosis after trimodal therapy in patients with locally advanced squamous cell carcinoma of the oesophagus. Eur J Cancer. 2012;48(16):2977-82.

Stang A, Dragano N, Moebus S, Möhlenkamp S, Schmermund A, Kälsch H, et al. Midday naps and the risk of coronary artery disease: results of the heinz nixdorf recall study. Sleep. 2012;35(12):1705-12.

Stausberg J, Pritzkuleit R, Schmidt CO, Schrader T, Nonnemacher M. Indicators of data quality: revision of a guideline for networked medical research. Stud Health Technol Inform. 2012;180:711-5.

Taal HR, St Pourcain B, Thiering E, Das S, Mook-Kanamori DO, Warrington NM, et al. Common variants at 12q15 and 12q24 are associated with infant head circumference. Nat Genet. 2012;44(5):532-8.

Thielmann M, Pasa S, Wendt D, Price V, Marggraf G, Neuhäuser M, et al. Prognostic significance of cardiac troponin I on admission for surgical treatment of acute pulmonary embolism: a single-centre experience over more than 10 years. Eur J Cardiothorac Surg. 2012;42(6):951-7.

Thomas S, Pütter C, Weber S, Bornfeld N, Lohmann DR, Zeschnigk M. Prognostic significance of chromosome 3 alterations determined by microsatellite analysis in uveal melanoma: a long-term follow-up study. Br J Cancer. 2012;106(6):1171-6.

Trellakis S, Rydleuskaya A, Fischer C, Canbay A, Tagay S, Scherag A, et al. Low adiponectin, high levels of apoptosis and increased peripheral blood neutrophil activity in healthy obese subjects. Obes Facts. 2012;5(3):305-18.

Tsoi LC, Spain SL, Knight J, Ellinghaus E, Stuart PE, Capon F, et al. Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet. 2012;44(12):1341-8.

Volckmar AL, Bolze F, Jarick I, Knoll N, Scherag A, Reinehr T, et al. Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants. BMC Med Genomics. 2012;5:65.

Vonneilich N, Jöckel KH, Erbel R, Klein J, Dragano N, Siegrist J, et al. The mediating effect of social relationships on the association between socioeconomic status and subjective health - results from the Heinz Nixdorf Recall cohort study. BMC Public Health. 2012;12:285.

Weber DG, Johnen G, Bryk O, Jöckel KH, Brüning T. Identification of miRNA-103 in the Cellular Fraction of Human Peripheral Blood as a Potential Biomarker for Malignant Mesothelioma - A Pilot Study. PLoS ONE. 2012;7(1):e30221.

Wichmann HE, Kaaks R, Hoffmann W, Jöckel KH, Greiser KH, Linseisen J. [The German National Cohort]. Bundesgesundheitsblatt Gesundheitsforschung, Gesundheitsschutz. 2012;55(6-7):781-7.

Yoon MS, Katsarava Z, Obermann M, Fritsche G, Oezyurt M, Kaesewinkel K, et al. Prevalence of primary headaches in Germany: results of the German Headache Consortium Study. J Headache Pain. 2012;13(3):215-23.

Yoon MS, Manack A, Fritsche G, Obermann M, Diener HC, Moebus S, et al. Chronic Migraine (CM) and Chronic Tension-Type Headache Are Associated with Concomitant Frequent Back Pain. Neurology. 2012;78 1.

Zegers BS, Uiterwaal CC, Verpoorten CC, Christiaens MM, Kimpen JJ, de Jong-de Vos van Steenwijk CC, et al. Home screening for bacteriuria in children with spina bifida and clean intermittent catheterization. BMC Infect Dis. 2012;12:264.

Zimmer L, Hillen U, Livingstone E, Lacouture ME, Busam K, Carvajal RD, et al. Atypical melanocytic proliferations and new primary melanomas in patients with advanced melanoma undergoing selective BRAF inhibition. J Clin Oncol. 2012;30(19):2375-83.